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While close relatives of people with narcolepsy have a statistically higher risk of developing the disorder than do members of the general population, that risk remains low when compared to diseases that are purely genetic in origin.. Baclofen is a centrally acting GABA-beta agonist that is frequently used in pediatric patients for the treatment of dystonia, rigidity, and spasticity, which are associated with a variety of. Cataplexy treatments include antidepressants or a GABA-B agonist, gamma hydroxybutyrate (GHB). The phase IV clinical study analyzes which people take Baclofen and have Narcolepsy. A recent report of a murine model of narcolepsy-cataplexy suggests R-baclofen has potential efficacy against cataplexy Summary: Narcolepsy is found among people who take Baclofen, especially for people who are female, 50-59 old. Baclofen is a muscle relaxant that offers promising results in improving daytime wakefulness, sleeping patterns, and cataplexy in people with narcolepsy. Narcolepsy with cataplexy is estimated to affect about one in every 3,000 Americans. Those with cataplexy have spells of muscle. In this review, we described few conditions of cataplexy not related to narcolepsy. Background: Narcolepsy is a disabling sleep-wake disorder characterized by the pentad symptoms of excessive daytime sleepiness, sleep paralysis, sleep fragmentation, sleep-related hallucinations, and cataplexy. Most doctors recommend trying modafinil ( Provigil) or armodafinil. Therefore, it is essential disconnecting cataplexy from narcolepsy especially in pediatric population and after use of a few medications. A number of medications can help a person stay awake. There is no curative therapy for narcolepsy. More cases without cataplexy are also likely to exist. Treatment is therefore symptom directed In narcolepsy without cataplexy, the main symptom is sudden sleepiness. GHB is the most effective treatment for cataplexy, but is expensive and can have significant side effects. 4 We report on two patients with narcolepsy-cataplexy who experienced significant. However, more research is needed.

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